The Getty Transplant
What could go wrong?
On December 13, Jeff Getty received a transfusion of straw-colored fluid containing two types of baboon cells:

Critics of the experiment say it was not backed by enough animal testing, and even the doctors involved consider it of a long shot. What were the obstacles to success?

This crucial second step has apparently not occurred: Few, if any, of the baboon cells were alive a month after the transplant, Getty's doctor reported. But even if that step did suceed, the transplant would have faced other obstacles: What could account for Getty's improved health since the transplant? It may be the natural variability if end-stage AIDS. Or, his doctor speculated, it could be the pre-transplant radiation intended to prevent rejection of the new cells.

Or his health could be due to the simple -- but profound -- improvement in his mood raised by the hope that the transplant would actually control his disease, according to his doctor.

To do future baboon-cell tranplants, doctors would need further federal approval. They would probably use stronger anti-rejection drugs, more radiation, or both, to prevent rejection of the baboon cells. No such experiments are planned at this point.

Been Done Before
Most people associate xenotransplantation with the abortive effort to transplant a baboon heart into "Baby Fae" in the early 1980s. But some inter-species transplants have been more successful.

Instead of the expensive, high-tech transplant approach, some scientists are taking a closer look at people who naturally resist the deadly HIV.

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