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Gene Therapy: The eyes have it!



Bainbridge, James, et al, Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis, N Engl J Med 2008 0: NEJMoa0802268.

Miller, Joan W. Preliminary Results of Gene Therapy for Retinal Degeneration, N Engl J Med 2008 0: NEJMe0803081.

Maguire, Albert M. et al, Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis, N Engl J Med 2008 0: NEJMoa0802315.

CHINESE GENE THERAPY: Gendicine's Efficacy: Hard to Translate, Hao Xin, Science 24 November 2006: Vol. 314. no. 5803, p. 1233.

HUMAN GENE THERAPY 16:1016-1027 (September 2005), Current Status of Gendicine in China: Recombinant Human Ad-p53 Agent for Treatment of Cancers, ZHAOHUI PENG.

Flt3L and TK gene therapy eradicate multifocal glioma in a syngeneic glioblastoma model, Gwendalyn D. King et al, Neuro-oncol 2008 10: 19-31

Gene Therapy “Trains” Immune System to Destroy Brain Cancer Cells and Reverses Behavioral Deficits

Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain, Benjamin Storek, Matthias Reinhardt, Cheng Wang, William G. M. Janssen, Nina M. Harder, Michaela S. Banck, John H. Morrison and Andreas S. Beutler, Proceedings of the National Academy of Sciences 105: 1055-1060; published online as 10.1073/pnas.0708003105.

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors, Amanda M. Haidet et al, PNAS, March 18, 2008.

Gene Therapy for Human Genetic Disease? Theodore Friedmann and Richard Roblin, Science, March 3, 1972.

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To conquer cancer.
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Megan Anderson, project assistant; Terry Devitt, editor; S.V. Medaris, designer/illustrator; David Tenenbaum, feature writer; Amy Toburen, content development executive

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